Literature database
Orthomolecular prevention and complementary treatment of cancer
This database was composed by drs. Ed Woerlee and made available on the web by the Dutch Foundation for Orthomolecular Education S.O.E.
The database contains randomised and/or randomised + double-blinded-placebo-controlled human clinical studies on the complementary orthomolecular treatment of existing cancer added to orthodox treatment. Also, it contains some only double-blind-placebo-controlled or prospective randomised clinical studies. For experienced researchers and doctors the list may give strong indications where to find more reliable evidence.
This summary is derived from a substantial innovative randomised survey on existing human cancer made by Dr. E. Valstar, Stadhouderslaan 30, 2517 HZ The Hague, The Netherlands. It has here been extended with meta-analyses, with randomised and prospective studies on cancer prevention and with randomised studies on nutritional support. However, despite the length of the list it still contains no case-control studies, only a few reviews, none of the many hundreds spectacular orthomolecular non-randomized or non-blinded studies on existing cancer, nor the interesting randomised psychological support studies or any animal or in-vitro studies.
When using the PubMed (www.ncbi.nlm.nih.gov/Pubmed) or Gateway (http://gateway.nlm.nih.gov/gw/Cmd) medical databases, an abstract can be found by searching via the author name, combined with first page and year of publication, but sometimes the additional word random* or more search data from the table are needed. Any additional randomised study for incorporation in the list, or errata will be gladly welcomed. The table contains 810 randomised studies, has been updated until 20 April 2003, but could, as some tests showed, presently already been tripled. The option "Related articles" in the PubMed database is very useful.
Disclaimer: The list helps researchers to reduce the tedious work of scanning the literature for more reliable evidence, and is not intended for patients or inexperienced practitioners to derive medical treatments from it. Some compound may give dangerous side effects when used excessively, like e.g. the retinoids and hydroxy-vit. D3-metabolites, and as is well known there are maximum limits to the application of especially Vit. A, D3 and B6, selenium, etc.
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